Resume

Experience

Expertise, focus, and other positions

Clinical expertise:

• Expertise center Hearing and Genes: a multidisciplinary approach to hereditary hearing loss;
• Cochlear implants in children;
• Complex Diagnostics of hearing in children;
• Tinnitus and hyperacusis.
• Working on the accessibility of care and setting-up care networks.

Academic focus:

• Hearing and Genes: perceptual consequences of genetic mutations and the underlying mechanisms; site-of- lesion testing; (see e.g. research output)
• Inner ear therapy & Clinical trials
• Phase 1 & 2 Clinical trial on a new medicine for sudden deafness (see press release)
• Cochlear implants and middle ear implants: indication criteria, output measurements, and functional outcome measures.
• Deep auditory profiling; how to describe auditory performance best.

Other positions

• NVKF Commissie Wetenschap en Innovatie
• Editor of special issue of Genes, Functional Otogenetics
• Scientific advisor audiology at ENT clinical
• (co-)Editor of the online audiology book https://audiologieboek.nl/

Radboud University Medical Center

University Medical Center Groningen

In this training position at the University Audiological Centrum Groningen I spent 1.5 years of training at Pento Audiologisch Centrum, Zwolle. In this position I was part of the taskgroup ‘tinnituszorg’ of the FENAC. I have also been a board member of KLIFOP, and represented the medical physicists in training. As part of this representation, I have taken a position in the committee science and innovation of the Nederlandse Vereniging Klinische Fysica (NVKF). Furthermore, I am part of the audiologist training network of the Medical Physicists Netherlands, the KKAu.

My research focus was aimed at tinnitus and took part from 2014-2016 in the workgroup Neuroimaging of the COST action TINNET (BM1306), developing standards for neuroimaging studies and probing the neurobiological entity of the defined subtypes by large-scale analyses of neuroimaging data.

MRC Institute of Hearing Research, Nottingham

As a postdoc I worked with Katrin Krumbholz on ultrahigh resolution fMRI of the auditory cortex (together with the SPMMRC) and studied the frequency selectivity of the cortex using EEG methods.

University of Groningen

PhD project on fMRI of tinnitus at the faculty of Medical Sciences, University Medical Center Groningen. Promotor(s): prof.dr. P. van Dijk and dr. ir. E. de Kleine. Date : 31 March 2010, 16.15h. PDF

Education

University of Groningen

MSc Applied Physics, master Biomedical Engineering — Medical Imaging and Instrumentation. Masters thesis: Perfusion Imaging using Arterial Spin Labeling. Graduation: May 2005

Wessel Gansfort College

Grants and Prizes

2011 Nomination best PhD thesis (BCN)
2011 Travel grant (Guarantors of Brain) [800 GBP]
2010 Nomination best PhD thesis (BCN) [500 GBP]
2011 Thesis grants [3500 eur]

Educational Activities

2018 – now | Lecturer Minor Clinical Genomics, Otogenetics, Radboudumc
2015 – 2017 | Lecturer Capita “From sound to hearing”, Biological Physics, University of Groningen
2013 – 2017 | Lecturer Vector Calculus and Mathematics for Neuroscientists, Graduate school Behavioral and Cognitive Neurosciences, University of Groningen
2005 – 2009 | Lecturer fMRI Course Research Master, Graduate school Behavioral and Cognitive Neurosciences, University of Groningen

Digital Presence

Platform	Link
Web of Science ResearcherID	https://publons.com/researcher/S-6334-2017/
ORCID	https://orcid.org/0000-0001-9397-7766
Publons	https://publons.com/researcher/1279367/cris-lanting/
LinkedIN:	http://www.linkedin.com/in/crislanting
Google Scholar	https://scholar.google.com/citations?user=N9sgDFUAAAAJ&hl

Research output

last modified: July 2023 Note, this is work in progress (i.e., Jekyll_scholar plugin + Bib may work but the formatting may need some TLC.).

2008

1. Lanting, C. P., De Kleine, E., Bartels, H., & Van Dijk, P. (2008). Functional Imaging of Unilateral Tinnitus Using fMRI. Acta Oto-Laryngologica, 128(4), 415–421. https://doi.org/10.1080/00016480701793743

2009

1. Lanting, C. P., de Kleine, E., & van Dijk, P. (2009). Neural Activity Underlying Tinnitus Generation: Results from PET and fMRI. Hearing Research, 255(1-2), 1–13. https://doi.org/10.1016/j.heares.2009.06.009

2010

1. Lanting, C. P., de Kleine, E., Eppinga, R. N., & van Dijk, P. (2010). Neural Correlates of Human Somatosensory Integration in Tinnitus. Hearing Research, 267(1-2), 78–88. https://doi.org/10.1016/j.heares.2010.04.006
2. Crippa, A., Lanting, C. P., van Dijk, P., & Roerdink, J. B. T. M. (2010). A Diffusion Tensor Imaging Study on the Auditory System and Tinnitus. The Open Neuroimaging Journal, 4, 16–25. https://doi.org/10.2174/1874440001004010016

2013

1. Lanting, C. P., Briley, P. M., Sumner, C. J., & Krumbholz, K. (2013). Mechanisms of Adaptation in Human Auditory Cortex. Journal of Neurophysiology, 110(4), 973–983. https://doi.org/10.1152/jn.00547.2012

2014

1. Lanting, C. P., de Kleine, E., Langers, D. R. M., & van Dijk, P. (2014). Unilateral Tinnitus: Changes in Connectivity and Response Lateralization Measured with fMRI. PLoS ONE, 9(10), e110704. https://doi.org/10.1371/journal.pone.0110704
2. Hall, D., Lanting, C., & Hartley, D. (2014). Using fMRI to Examine Central Auditory Plasticity. In T. D. Papageorgiou, G. I. Christopoulos, & S. M. Smirnakis (Eds.), Advanced Brain Neuroimaging Topics in Health and Disease - Methods and Applications. InTech. https://doi.org/10.5772/58262

2016

1. van Dijk, P., Başkent, D., Gaudrain, E., de Kleine, E., Wagner, A., & Lanting, C. (Eds.). (2016). Physiology, Psychoacoustics and Cognition in Normal and Impaired Hearing (Number Volume 894). Springer.
2. Lanting, C., WoźAniak, A., van Dijk, P., & Langers, D. R. M. (2016). Tinnitus- and Task-Related Differences in Resting-State Networks. In P. van Dijk, D. Başkent, E. Gaudrain, E. de Kleine, A. Wagner, & C. Lanting (Eds.), Physiology, Psychoacoustics and Cognition in Normal and Impaired Hearing (Vol. 894, pp. 175–187). Springer International Publishing. https://doi.org/10.1007/978-3-319-25474-6_19

2019

1. Besle, J., Mougin, O., Sánchez-Panchuelo, R.-M., Lanting, C., Gowland, P., Bowtell, R., Francis, S., & Krumbholz, K. (2019). Is Human Auditory Cortex Organization Compatible With the Monkey Model? Contrary Evidence From Ultra-High-Field Functional and Structural MRI. Cerebral Cortex (New York, N.Y.: 1991), 29(1), 410–428. https://doi.org/10.1093/cercor/bhy267
2. Smits, J. J., Oostrik, J., Beynon, A. J., Kant, S. G., de Koning Gans, P. A. M., Rotteveel, L. J. C., Klein Wassink-Ruiter, J. S., Free, R. H., Maas, S. M., van de Kamp, J., Merkus, P., Koole, W., Feenstra, I., Admiraal, R. J. C., Lanting, C. P., Schraders, M., Yntema, H. G., Pennings, R. J. E., & Kremer, H. (2019). De Novo and Inherited Loss-of-Function Variants of ATP2B2 Are Associated with Rapidly Progressive Hearing Impairment. Human Genetics, 138(1), 61–72. https://doi.org/10.1007/s00439-018-1965-1

2020

1. Smits, J. J., van Beelen, E., Weegerink, N. J. D., Oostrik, J., Huygen, P. L. M., Beynon, A. J., Lanting, C. P., Kunst, H. P. M., Schraders, M., Kremer, H., de Vrieze, E., & Pennings, R. J. E. (2020). A Novel COCH Mutation Affects the vWFA2 Domain and Leads to a Relatively Mild DFNA9 Phenotype. Otology & Neurotology, Publish Ahead of Print. https://doi.org/10.1097/MAO.0000000000003004
2. de Bruijn, S. E., Smits, J. J., Liu, C., Lanting, C. P., Beynon, A. J., Blankevoort, J., Oostrik, J., Koole, W., de Vrieze, E., Cremers, C. W. R. J., Cremers, F. P. M., Roosing, S., Yntema, H. G., Kunst, H. P. M., Zhao, B., Pennings, R. J. E., & Kremer, H. (2020). A RIPOR2 In-Frame Deletion Is a Frequent and Highly Penetrant Cause of Adult-Onset Hearing Loss. Journal of Medical Genetics, jmedgenet-2020–106863. https://doi.org/10.1136/jmedgenet-2020-106863
3. Koops, E. A., Renken, R. J., Lanting, C. P., & van Dijk, P. (2020). Cortical Tonotopic Map Changes in Humans Are Larger in Hearing Loss Than in Additional Tinnitus. Journal of Neuroscience, 40(16), 3178–3185. https://doi.org/10.1523/JNEUROSCI.2083-19.2020

2021

1. Wasmann, J.-W. A., Lanting, C. P., Huinck, W. J., Mylanus, E. A. M., van der Laak, J. W. M., Govaerts, P. J., Swanepoel, D. W., Moore, D. R., & Barbour, D. L. (2021). Computational Audiology: New Approaches to Advance Hearing Health Care in the Digital Age. Ear and Hearing, 42(6), 1499–1507. https://doi.org/10.1097/AUD.0000000000001041
2. Smits, J. J., de Bruijn, S. E., Lanting, C. P., Oostrik, J., O’Gorman, L., Mantere, T., DOOFNL Consortium, Cremers, F. P. M., Roosing, S., Yntema, H. G., de Vrieze, E., Derks, R., Hoischen, A., Pegge, S. A. H., Neveling, K., Pennings, R. J. E., & Kremer, H. (2021). Correction to: Exploring the Missing Heritability in Subjects with Hearing Loss, Enlarged Vestibular Aqueducts, and a Single or No Pathogenic SLC26A4 Variant. Human Genetics. https://doi.org/10.1007/s00439-021-02377-x
3. Smits, J. J., de Bruijn, S. E., Lanting, C. P., Oostrik, J., O’Gorman, L., Mantere, T., DOOFNL Consortium, Cremers, F. P. M., Roosing, S., Yntema, H. G., de Vrieze, E., Derks, R., Hoischen, A., Pegge, S. A. H., Neveling, K., Pennings, R. J. E., & Kremer, H. (2021). Exploring the Missing Heritability in Subjects with Hearing Loss, Enlarged Vestibular Aqueducts, and a Single or No Pathogenic SLC26A4 Variant. Human Genetics. https://doi.org/10.1007/s00439-021-02336-6
4. Chen, T., Rohacek, A. M., Caporizzo, M., Nankali, A., Smits, J. J., Oostrik, J., Lanting, C. P., Kücük, E., Gilissen, C., van de Kamp, J. M., Pennings, R. J. E., Rakowiecki, S. M., Kaestner, K. H., Ohlemiller, K. K., Oghalai, J. S., Kremer, H., Prosser, B. L., & Epstein, D. J. (2021). Cochlear Supporting Cells Require GAS2 for Cytoskeletal Architecture and Hearing. Developmental Cell, 56(10), 1526–1540.e7. https://doi.org/10.1016/j.devcel.2021.04.017

2022

1. Velde, H. M., Reurink, J., Held, S., Li, C. H. Z., Yzer, S., Oostrik, J., Weeda, J., Haer-Wigman, L., Yntema, H. G., Roosing, S., Pauleikhoff, L., Lange, C., Whelan, L., Dockery, A., Zhu, J., Keegan, D. J., Farrar, G. J., Kremer, H., Lanting, C. P., … Pennings, R. J. E. (2022). Usher Syndrome Type IV: Clinically and Molecularly Confirmed by Novel ARSG Variants. Human Genetics, 141(11), 1723–1738. https://doi.org/10.1007/s00439-022-02441-0
2. Lanting, C., Snik, A., Leijendeckers, J., Bosman, A., & Pennings, R. (2022). Genetic Hearing Loss Affects Cochlear Processing. Genes, 13(11), 1923. https://doi.org/10.3390/genes13111923
3. Maier, H., Lenarz, T., Agha-Mir-Salim, P., Agterberg, M. J. H., Anagiotos, A., Arndt, S., Ball, G., Bance, M., Barbara, M., Baumann, U., Baumgartner, W., Bernardeschi, D., Beutner, D., Bosman, A., Briggs, R., Busch, S., Caversaccio, M., Dahm, M., Dalhoff, E., … Snik, A. (2022). Consensus Statement on Bone Conduction Devices and Active Middle Ear Implants in Conductive and Mixed Hearing Loss. Otology & Neurotology: Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. https://doi.org/10.1097/MAO.0000000000003491
4. Robijn, S. M. M., Smits, J. J., Sezer, K., Huygen, P. L. M., Beynon, A. J., van Wijk, E., Kremer, H., de Vrieze, E., Lanting, C. P., & Pennings, R. J. E. (2022). Genotype-Phenotype Correlations of Pathogenic COCH Variants in DFNA9: A HuGE Systematic Review and Audiometric Meta-Analysis. Biomolecules, 12(2), 220. https://doi.org/10.3390/biom12020220

2023

1. Velde, H. M., Homans, N. C., Goedegebure, A., Lanting, C. P., Pennings, R. J. E., & Kremer, H. (2023). Analysis of Rotterdam Study Cohorts Confirms a Previously Identified RIPOR2 In-Frame Deletion as a Prevalent Genetic Factor in Phenotypically Variable Adult-Onset Hearing Loss (DFNA21) in the Netherlands. Journal of Medical Genetics, jmg-2023–109146. https://doi.org/10.1136/jmg-2023-109146
2. Vreman, J., Lemson, J., Lanting, C., van der Hoeven, J., & van den Boogaard, M. (2023). The Effectiveness of the Interventions to Reduce Sound Levels in the ICU: A Systematic Review. Critical Care Explorations, 5(4), e0885. https://doi.org/10.1097/CCE.0000000000000885
3. Velde, H. M., Huizenga, X. J. J., Yntema, H. G., Haer-Wigman, L., Beynon, A. J., Oostrik, J., Pegge, S. A. H., Kremer, H., Lanting, C. P., & Pennings, R. J. E. (2023). Genotype and Phenotype Analyses of a Novel WFS1 Variant (c.2512C>T p.(Pro838Ser)) Associated with DFNA6/14/38. Genes, 14(2), 457. https://doi.org/10.3390/genes14020457